Friday, December 16, 2011

Gov't to adopt strict new limits on chimp research

FILE - In this Jan. 31, 1961 file photo, Ham, the first higher primate launched into outer space, is comforted by an unidentified man on the deck of a rescue ship after the splashdown in the Atlantic Ocean. Chimpanzees should hardly ever be used for medical research, a prestigious scientific group told the government Thursday _ advice that means days in the laboratory may be numbered for humans' closest relatives. The Institute of Medicine stopped short of recommending the outright ban that animal rights activists had pushed. Instead, it urged strict limits that would make invasive experiments with chimps essentially a last resort, saying today's more advanced research tools mean the primates' use only rarely will be necessary enough to outweigh the moral costs. (AP Photo, File)

FILE - In this Jan. 31, 1961 file photo, Ham, the first higher primate launched into outer space, is comforted by an unidentified man on the deck of a rescue ship after the splashdown in the Atlantic Ocean. Chimpanzees should hardly ever be used for medical research, a prestigious scientific group told the government Thursday _ advice that means days in the laboratory may be numbered for humans' closest relatives. The Institute of Medicine stopped short of recommending the outright ban that animal rights activists had pushed. Instead, it urged strict limits that would make invasive experiments with chimps essentially a last resort, saying today's more advanced research tools mean the primates' use only rarely will be necessary enough to outweigh the moral costs. (AP Photo, File)

This undated photo provided by the Wildlife Way Station shows Booie the chimpanzee. Booie who kicked a smoking habit and used sign language to beg for candy has died at a California animal refuge. Martine Colette of the Wildlife WayStation says Booie, was being treated for a heart condition when he died Saturday, Dec. 11, 2011, at 44. The chimp had been living at the animal sanctuary near Los Angeles since 1995, after he retired from a research lab. Colette says she turned Booie into a non-smoker but couldn't fix his sweet tooth. (AP Photo/Wildlife Way Station, Dave Welling)

(AP) ? The government on Thursday said it would adopt strict new limits on using chimpanzees in medical research, after a prestigious scientific group recommended that experiments with humans' closest relative be done only as a last resort.

The National Institutes of Health agreed that science has advanced enough that chimps seldom would be needed to help develop new medicines.

NIH Director Francis Collins temporarily barred new federal funding for research involving chimps, and said a working group will review about 37 ongoing projects involving the animals to see if they should be phased out.

Chimps' similarity to people "demands special consideration and respect," Collins said.

These apes' genetic closeness to humans has long caused a quandary. It's what has made them so valuable to scientists for nearly a century. They were vital in creating a vaccine for hepatitis B, for example, and even were shot into space to make sure the trip wouldn't kill the astronauts next in line.

But that close relationship also has had animal rights groups arguing that using chimps for biomedical research is unethical, even cruel.

Chimp research already was dwindling fast as scientists turned to less costly and ethically charged alternatives.

Thursday's decision was triggered by an uproar last year over the fate of 186 semi-retired research chimps that the NIH, to save money, planned to move from a New Mexico facility to an active research lab in Texas.

Where and how to house those animals ? and others scattered around the country who probably no longer will be needed ? are among the issues that Collins said a government working group will decide as it determines how to implement the new research restrictions.

The Institute of Medicine's recommendation on Thursday stopped short of the outright ban that animal rights activists had pushed. Instead, it urged strict limits on biomedical research ? testing new drugs or giving animals a disease ? that would allow using chimps only if studies could not be done on other animals or people themselves, and if foregoing the chimp work would hinder progress against life-threatening or debilitating conditions.

The panel advised the government to limit use of chimps in behavioral and genetic research as well, saying such studies must provide insights that otherwise are unattainable ? and use techniques that minimize any pain or distress.

"We understand and feel compelled by the moral cost of using chimpanzees in research," said bioethicist Jeffrey Kahn of Johns Hopkins University, who chaired the Institute of Medicine panel. "We have established criteria that will set the bar quite high for justification of the use of chimpanzees."

The U.S. is one of only two countries known to still conduct medical research with chimpanzees; the other is Gabon, in Africa. The European Union essentially banned such research last year.

Here, too, the practice was becoming uncommon. The Institute of Medicine's investigation found over the past 10 years, the NIH has paid for just 110 projects of any type that involved chimps. There are not quite 1,000 chimps available for medical research in the country.

While it's impossible to say how many have been used in privately funded pharmaceutical research, the industry is shifting to higher-tech and less costly research methods. One drug company, GlaxoSmithKline, adopted an official policy ending its use of great apes, including chimpanzees, in research.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2011-12-15-Chimp%20Research/id-36bbfb9de9434db89bc0d526f1292cd0

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